Sergey Grigorenko

Rak Legkikh V Sochetanii S Tuberkulezom: Kliniko-morfologicheskie Osobennosti Zabolevaniya I Analiz Faktorov, Vliyayushchikh Na Vyzhivaemost' Sergey Grigorenko Russian edition

Proanalizirovany dannye 62 bol'nykh rakom legkogo v sochetanii s razlichnymi formami tuberkuleza i 48 bol'nykh s diagnozom raka legkikh bez tuberkuleza. Dlya opredeleniya faktorov, vliyayushchikh na prodolzhitel'nost' zhizni u bol'nykh rakom legkogo v sochetanii s tuberkulezom i vyyavleniya otnositel'noy znachimosti (vazhnosti) etikh faktorov ispol'zovali metod iskusstvennykh neyronnykh setey. Izuchenie otnositel'nogo vliyaniya otdel'nykh prediktorov na iskhod zabolevaniya pokazalo, chto naibol'shee otritsatel'noe vliyanie na vyzhivaemost' okazyvalo nalichie u bol'nogo zapushchennoy stadii raka, i, naoborot, svoevremenno vyyavlennyy i radikal'no prolechennyy rak imel otchetlivuyu polozhitel'nuyu sinapticheskuyu svyaz' s bolee prodolzhitel'nym periodom zhizni. Ukhudshali vyzhivaemost' nalichie aktivnosti tuberkuleza, otkaz ot khirurgicheskogo lecheniya, tsentral'naya lokalizatsiya raka, nizkaya stepen' gistologicheskoy differentsirovki opukholi i pozhiloy vozrast. Pri ispol'zovanii dannoy modeli dlya prognozirovaniya iskhodov naibol'shaya veroyatnost' pravil'nogo prognoza (90,9% v testiruemoy vyborke) byla dlya perioda dozhitiya menee 12 mesyatsev, s men'shey tochnost'yu sistema sposobna predskazat' trekhletnyuyu i pyatiletnyuyu vyzhivaemost'.