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Novel Molecular Targets for Genistein in Prostate Cancer Cells James Kumi-diaka
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Novel Molecular Targets for Genistein in Prostate Cancer Cells
James Kumi-diaka
Genistein is a major isoflavone constituent of soy that has been shown to inhibit growth proliferation and induce apoptosis in cancer cells. The mechanism of genistein-induced cell death and potential molecular targets for genistein in LNCaP prostate cancer cells was investigated using several techniques. The chemosensitivity of genistein towards prostate cancer cells was investigated using the ATP and MTS assays and apoptosis induction was determined using apoptosis and caspase assays. Several molecular targets were also identified using cDNA microarray and RT-PCR analysis.
| Media | Books Paperback Book (Book with soft cover and glued back) |
| Released | June 22, 2010 |
| ISBN13 | 9783838338842 |
| Publishers | LAP Lambert Academic Publishing |
| Pages | 100 |
| Dimensions | 225 × 6 × 150 mm · 167 g |
| Language | German |