Salman Bin Hosain

Handbook of Sustained Release Dosage Form: Pharmaceutical Aspects of Sustained Release Dosage Form Salman Bin Hosain

The rate at which a drug is released from a resinate is dependent on many factors. In many cases the rate is sufficiently slow that the resulting effect is an extended or sustained release over many hours. Further modification can be achieved by the use of coatings that restrict the release, or control the site of release. Examples of drugs where this technique is currently used include dextromethorphan(coated),diclofenac, and nicotine. The resinate will be a solid, with similar characteristics to the original ion exchange resin powder and, as such, can be formulated into any of the traditional solid dosage forms. Time Release Technology also known as Sustained-release (SR), extended-release (ER, XR, or XL), time-release or timed-release, controlled-release (CR), or continuous-release (CR or Contin) pills are tablets or capsules formulated to dissolve slowly and release a drug over time. The advantages of sustained-release tablets or capsules are that they can often be taken less frequently than instant-release formulations of the same drug, and that they keep steadier levels of the drug in the bloodstream