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Vliyanie Agonistov Gamk Na Obuchenie: Aspekty Neyrofarmakologii I Neyrofiziologii Evgeniya Zyablitseva Russian edition
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Vliyanie Agonistov Gamk Na Obuchenie: Aspekty Neyrofarmakologii I Neyrofiziologii
Evgeniya Zyablitseva
V rabote provedeno issledovanie vliyaniya neselektivnogo agonista GAMK-retseptorov fenibuta i selektivnogo agonista GAMKA-retseptorov gaboksadola (THIP) na protsess obucheniya. Na fone vvedeniya fenibuta uskoryaetsya vyrabotka oboronitel'nogo uslovnogo refleksa. Gaboksadol zhe ne okazyvaet vliyanie na skorost' vyrabotki uslovnogo refleksa. Sopostavlenie deystviya fenibuta i gaboksadola na skorost' vyrabotki uslovnogo tormoza vyyavilo razlichnuyu stepen' uchastiya GAMKA- i GAMKB-retseptorov v protsesse obucheniya. Na rannikh stadiyakh obucheniya vedushchaya rol' v vyrabotke uslovnogo tormoza, veroyatno, prinadlezhit GAMKB-retseptoram. GAMKA- retseptory uchastvuyut v vyrabotke uslovnogo tormoza na bolee pozdnikh stadiyakh obucheniya. Takim obrazom, metabotropnye retseptory, veroyatno, imeyut bol'shiy vklad v protsess obucheniya. Issledovanie svobodnogo povedeniya zhivotnykh v teste "otkrytoe pole" vyyavilo snizhenie trevozhnosti na fone vvedeniya fenibuta. Statisticheskiy analiz aktivnosti neyronov na fone vvedeniya fenibuta pokazal povyshenie gruppovoy impul'satsii neyronov v del'ta-diapazone i snizhenie v diapazone teta.
| Media | Books Paperback Book (Book with soft cover and glued back) |
| Released | June 15, 2011 |
| ISBN13 | 9783844353099 |
| Publishers | LAP LAMBERT Academic Publishing |
| Pages | 160 |
| Dimensions | 150 × 9 × 225 mm · 256 g |
| Language | German |