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Identifikatsiya Novogo Belkovogo Nasledstvennogo Determinanta U Drozhzhey.: Priony Drozhzhey Kak Nasledstvennye Determinanty Belkovoy Prirody Tat'yana Rogoza Russian edition
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Identifikatsiya Novogo Belkovogo Nasledstvennogo Determinanta U Drozhzhey.: Priony Drozhzhey Kak Nasledstvennye Determinanty Belkovoy Prirody
Tat'yana Rogoza
Kniga posvyashchena kharakteristike yavleniya belkovoy nasledstvennosti, obnaruzhennogo v seredine 90-kh godov 20 veka u nizshikh eukariot. V osnove etogo fenomena lezhit konformatsionnoe prevrashchenie belkovoy molekuly,privodyashchee k vozniknoveniyu avtokataliticheski podderzhivaemogo konformera, nazyvaemogo prionom po analogii s infektsionnymi agentami belkovoy prirody mlekopitayushchikh, vyzyvayushchimi neizlechimye neyrodegenerativnye zabolevaniya. Naibolee izuchen s etoy tochki zreniya model'nyy geneticheskiy ob"ekt - drozhzhi-sakharomitsety, u kotorogo naydeno uzhe neskol'ko prionov. Issledovanie drozhzhevykh prionov imeet vazhnoe fundamental'noe znachenie, poskol'ku sushchestvenno rasshiryaet predstavleniya o mekhanizmakh nasledstvennosti. Krome togo, priony drozhzhey mogut sluzhit' v kachestve modeli dlya izucheniya molekulyarnykh mekhanizmov vozniknoveniya i podderzhaniya prionov u mlekopitayushchikh. Pomimo obshchey informatsii v knige podrobno opisana rabota, tsel'yu kotoroy bylo vyyasnenie prirody ranee neizvestnogo nekhromosomnogo nasledstvennogo determinanta drozhzhey.
| Media | Books Paperback Book (Book with soft cover and glued back) |
| Released | September 23, 2011 |
| ISBN13 | 9783844357905 |
| Publishers | LAP LAMBERT Academic Publishing |
| Pages | 120 |
| Dimensions | 150 × 7 × 225 mm · 197 g |
| Language | German |