![Faktor [psi+] I Mutatsii V Belke Sup35: Izucheniya Vliyaniya Ryada Aminokislotnykh Zamen V N-domene Belka Sup35 Na Podderzhanie I Stabil'nost' Faktora [psi+] - Galina Zhuravleva - Books - LAP LAMBERT Academic Publishing - 9783846524565 - October 24, 2011](https://imusic.b-cdn.net/images/item/original/565/9783846524565.jpg?galina-zhuravleva-2011-faktor-psi-i-mutatsii-v-belke-sup35-izucheniya-vliyaniya-ryada-aminokislotnykh-zamen-v-n-domene-belka-sup35-na-podderzhanie-i-stabil-nost-faktora-psi-paperback-book&class=scaled&v=1409226421)
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Faktor [psi+] I Mutatsii V Belke Sup35: Izucheniya Vliyaniya Ryada Aminokislotnykh Zamen V N-domene Belka Sup35 Na Podderzhanie I Stabil'nost' Faktora [psi+] Galina Zhuravleva Russian edition
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Faktor [psi+] I Mutatsii V Belke Sup35: Izucheniya Vliyaniya Ryada Aminokislotnykh Zamen V N-domene Belka Sup35 Na Podderzhanie I Stabil'nost' Faktora [psi+]
Galina Zhuravleva
Soglasno sovremennym predstavleniyam priony ? eto agenty belkovoy prirody, sposobnye peredavat'sya ot odnogo organizma k drugomu. Osobaya ukladka etikh belkov predstavlyaet soboy matritsu vtorogo roda, a imenno ikh struktura kopiruetsya za schyet izmeneniya konformatsii opredelyennykh kletochnykh polipeptidov. Odnoy iz naibolee udobnykh modeley dlya izucheniya prionov yavlyaetsya faktor [PSI+] drozhzhey Saccharomyces cerevisiae, kotoryy predstavlyaet soboy prionnuyu formu faktora terminatsii translyatsii eRF3 (Sup35p). V khode opisannykh v etoy rabote eksperimentov nam udalos' pokazat' razlichnye effekty aminokislotnykh zamen v N-domene Sup35p na stabil'nost' i podderzhanie faktora [PSI+], chast' iz nikh «usilivala» prion, nekotorye drugie, naprotiv, privodili k ego ischeznoveniyu iz kletok. Poluchennye nami rezul'taty pri ikh ekstrapolyatsii na priony mlekopitayushchikh mogut sluzhit' osnovoy dlya razrabotki lekarstv ot takikh zabolevaniy kak korov'e beshenstvo, Kuru, bolezn' Kreytsfel'da-Yakoba i t.d.
| Media | Books Paperback Book (Book with soft cover and glued back) |
| Released | October 24, 2011 |
| ISBN13 | 9783846524565 |
| Publishers | LAP LAMBERT Academic Publishing |
| Pages | 76 |
| Dimensions | 150 × 5 × 225 mm · 131 g |
| Language | German |
![Cover for Galina Zhuravleva · Geneticheskiy Kontrol' Terminatsii Translyatsii U Eukariot: Identifikatsiya Belkov Erf3/sup35 I Pab1, Kak Uchastvuyushchikh V Protsesse Terminatsii (Paperback Book) [Russian edition] (2011)](https://imusic.b-cdn.net/images/item/original/731/9783843324731.jpg?galina-zhuravleva-2011-geneticheskiy-kontrol-terminatsii-translyatsii-u-eukariot-identifikatsiya-belkov-erf3-sup35-i-pab1-kak-uchastvuyushchikh-v-protsesse-terminatsii-paperback-book&class=scaled&v=1409948202)